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Article: HRT Cream - A new base to deliver your hormone therapy

HRT Cream - A new base to deliver your hormone therapy

XenCare HRT Cream Base

Xenex Labs is introducing its proprietary HRT Cream that is formulated to provide a stable and effective vehicle for bioidentical hormones topically. This base is paraben-free, made without dyes nor fragrances, it is non-occlusive, and non-greasy and these properties allow the base to be versatile - it can be used vaginally, topically, or rectally.



Deionized Water, Glyceryl Stearate (and) Laureth-23, Glycerin, Glycine Soja Oil, Stearic Acid, Oleic Acid, Cetyl Alcohol, Paraffinum Liquidum, Lanolin, Laneth-16 (and) Ceteth-16 (and) Oleth-16 (and) Steareth-16, Triethanolamine, Tocopheryl Acetate, Propylene (and) Diazolindinyl Urea (and) Iodopropynyl, Butylcarbamate, Carbomer, Retinyl Palmitate, Aloe Barbadensis Leaf Powder



XenCare HRT Cream is a white, homogeneous, unscented light viscosity cream.

pH  6.0-7.5
Specific Gravity 0.9 - 1.1 g/cm3
Viscosity 135,000 - 300,000 cPs
Solubility Water


Sample Formula

Estriol 0.1% Vaginal Cream
Makes 100g
This preparation should be prepared in a vertical airflow hood in a biological safety cabinet or barrier isolation technology
Estriol powder 100mg
Propylene glycol 3mL
XenCare HRT Cream qs 100g
Used for estrogen hormone replacement therapy
Compounding Procedure
1. Calculate the required quantity of each ingredient for the total amount to be prepared
2. Accurately weight and/or measure each ingredient
3. Mix the estriol powder with the propylene glycol to form a smooth paste
4. Geometrically, add the Xenex HRT Cream and bring to final weight, mix well after each addition
5. Package and label
Packaging and Labeling
For vaginal use, not to be taken by mouth, keep out of reach of children, pregnant women must not handle
this medicine
Beyond Use Date


 Disclaimer: Xenex Laboratories Inc. has provided the formula and instructions above as a model for educational purposes only on the basis of recognized compendia and texts or references. Xenex Laboratories Inc. takes no responsibility for the validity or accuracy of this information or for its safety or effectiveness, nor for any use thereof, which is at the sole risk of the licensed pharmacist. Adjustments may be needed to meet specific patient needs and in accordance with a licensed prescriber’s prescription. The pharmacist must employ appropriate tests to determine the stability of this suggested formula. Xenex Laboratories Inc., its owners, officers, agents, contractors, affiliates and employees cannot be held liable to any person or entity concerning claims, loss or damage caused by, or alleged to be caused by, directly or indirectly, the use or misuse of the information contained in this suggested formula. In all cases, it is the responsibility of the licensed pharmacist to know the law, to compound any finished product and to dispense these products in accordance with Health Canada and FDA guidelines and appropriate Provincial Drug Schedules and Provincial or Territorial Pharmacy Practice Standards. 

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